成人结核性脑膜炎强化治疗

NEnglJMed;:-January14,DOI:10./NEJMoaBACKGROUND

Tuberculousmeningitisisoftenlethal.Earlyantituberculosistreatmentandadjunctivetreatmentwithglucocorticoidsimprovesurvival,butnearlyonethirdofpatientswiththeconditionstilldie.WehypothesizedthatintensifiedantituberculosistreatmentwouldenhancethekillingofintracerebralMycobacteriumtuberculosisorganismsanddecreasetherateofdeathamongpatients.

Weperformedarandomized,double-blind,placebo-controlledtrialinvolvinghumanimmunodeficiencyvirus(HIV)–infectedadultsandHIV-uninfectedadultswithaclinicaldiagnosisoftuberculousmeningitiswhowereadmittedtooneoftwoVietnamesehospitals.We







































乌鲁木齐治白癜风最好的医院
北京治疗白癜风多少钱就够了